Research

Bodet, Charles; La, Vu Dang; Gafner, Stefan; Bergeron, Chantal; Grenier, Daniel. (2008) A licorice extract reduces lipopolysaccharide-induced pro-inflammatory cytokine secretion by macrophages and whole blood. Journal of Periodontology, 79(9): 1752-1761.
Objective: To test whether a carbon dioxide–supercritical extract of Glycyrrhiza uralensis (licorice) can reduce the periodontopathogen-induced inflammatory response.

E. E. Engelman and J.A. Venell, Efficacy Trends of an Aging U.S. Pharmacopeia Reference Dentifrice, J Dent Res 84 (Spec Iss A) 3257, 2005.
Objective: To compare the efficacy of a prototype all-natural silica/NaMFP dentifrice, a commercially purchased silica/NaMFP dentifrice and the current (and only available) USP Sodium Monofluorophosphate (1000ppm)/Silica Reference Dentifrice (Lot PTG 07-40).

D. Zero, J.R. Chin, S.A. Kelly, G.J. Eckert, J.A. Venell, and E.E. Engelman, Efficacy of Natural Toothpastes in an In situ Caries Model, J Dent Res 84 (Spec Iss A) 3259, 2005.
Objective: To evaluate the efficacy of two NaF silica base (whitening gel and whitening liquid gel) all-natural dentifrices in an in situ caries model clinical trial.

T.M. Hutchins, E.E. Engelman and B. Schemehorn, EFU Investigation of Natural Fluoride Mouthwashes vs. ADA Accepted Mouthwashes, J Dent Res 84 (Spec Iss A) 3266, 2005.
Objectives: 1) Evaluate the efficacy of two all-natural anticavity mouthwashes and two commercially available American Dental Association® Accepted anticavity mouthwashes using enamel fluoride uptake (EFU) and 2) Investigate fluoride mouthwash efficacy as a function of pH.

E.R. Dumans, E.E. Engelman, and J.A. Venell, In vitro Antibacterial Comparison of Dentifrices Claiming Antigingivitis and Gum-Healing Properties, J Dent Res 82 (Spec Iss A) 0389, 2003.
Objective: To compare the antibacterial efficacy of prototype antigingivitis toothpastes to currently marketed toothpaste products making gum-related claims, when tested vs. oral microorganisms of significance in an agar dilution MIC test.